Lithium toxicity inogona kunge yakakonzera chirwere chakakonzerwa nokuva nemitemo yakawanda muhutano hwako. Sezvo lithiamu inoshandiswa mushonga wekushandisa kwechiremba ndeyekusimudzira mafungiro , maitiro akawanda anowanikwa pakati pevanhu vane bipolar disorder. Mukuwedzera, vanhu vanogara nemumwe munhu anotora lithium angave ari pangozi yekusaziva kusanganisa uye kuora.
Izvi zvakakosha kune vanhu vanotora mishonga iyi kuti vazive zviratidzo zve lithiamu inongo.
Vadiwa neshamwari vanofanirawo kudzidziswa nezvezviratidzo kuitira kuti vakwanise kukubatsira kana iwe usingakwanise kuzvibatsira.
Kuedzwa
Chimwe chezvikonzero zvinoita kuti vanachiremba varambe vachiongorora ropa nekuda kwevanhu vanotora lithium ndeyokuti firati pakati peyero inoshanda uye inonzi cheseti inonyanya kuwanda - uye chii chakachengeteka, chiitiko chinoshanda kune mumwe munhu chinogona kuva chinotyisa kune imwe.
Maererano neU.S. Food and Drug Administration (FDA), kazhinji , chido chakanaka chiri 0.6 kusvika 1.2 mEq / L. Zvisinei, vanotaura kuti, "Varwere vasinganzwisisiki neLithium vanogona kuratidza zviratidzo zvinotyisa kune serum iri pasi pe1 mEq / L."
Iyo yakakwirira senyoka yepamusoro, yakanyanya kuvepo ichava nemigumisiro miviri uye kuonekwa kwezviratidzo zvehutu (inonziwo lithium inodhaka).
Mhando dzeLithium Toxicity
Kune mhando mitatu ye lithiamu inonyanya: yakaoma, isingagumi, uye yakaoma pane zvisingaperi.
Acute
Izvi zvinowanzoitika apo mumwe munhu asiri kutora lithium.
Izvi zvinogona kuitika apo nhengo yemhuri inotora mapiritsi kubva mubhodhoro risina kunaka, apo mwana apinda mumishonga yemubereki, kana muedzo wokuzviuraya.
Maererano nevanotsvakurudza Timmer uye Sands, tsvina yakawanda inogona kutakura zvishoma zvishoma nezvehutano uye zviratidzo zvishoma kudarika zvimwewo, zvichienderana nemari yakatorwa.
Izvi, zvinoti, ndeyokuti lithi lithium ichabuda kunze kwemuviri nokukurumidza mune mumwe munhu ane chirongwa chisina kushandiswa ku lithiamu.
Zviratidzo zvinononoka zvinosanganisira zvirwere, chirwere, uchetura, kurwadziwa mumimba, kurutsa, uye kushaya simba. Zviratidzo zvakanyanya zvinogona kusanganisira kudengenyeka kwemaoko, ataxia, misi miviri, kutaura kwakanyanyisa, nystagmus, kugumburwa, coma uye, mune zvisingawanzoitika, zvinetso zvemwoyo.
Zvichienderana nezvakawanda zvakatorwa uye nokukurumidza kuwedzerwa kwe lithiamu kunowanikwa, kurapwa kunogona kusanganisira kuva nemimba yako inoputika, inopisa mvura, uye mafungiro dialysis, pakati pevamwe. Kazhinji, chirevo chacho chakanaka kunze kwekuti zvirwere zvemitsipa zviratidzo zvikaonekwa, pane izvozvi zvinogona kuva nezvinetso zvemazuva mazhinji.
Chronic
Nzira isingagumi yekudhakwa kweitroum inowanikwa kune vanhu vanotora lithiamu zuva rega rega asi seramu yeropa ropa yakasvikira mukati mehuni. Zvimwe zvinokonzera kuwedzera kuwedzerwa, kushaya mvura, kupindirana nemimwe mishonga, uye zvinetso nemishonga.
Kusiyana nehethiyumu inonzi lithium poisoning, varwere vane chronic lithium toxicity havawanzove nedumbu uye matumbo ematambudziko. Zviratidzo zvinowanzobatanidza kutaura kusinganzwisisiki, kudengenyeka, uye kuwedzera mafungiro.
Zvisinei, chirwere chisingaperi chineimhonyi hachiwanzoonekwa kare kupfuura mamwe maitiro.
Zvimwe zviratidzo zvakakomba zvinogona kuonekwa mamiriro acho asati aonekwa. Izvi zvinogona kusanganisira zvinetso zvekuyeuka uye kumwe kukanganisika kwekufungisisa, matambudziko makuru ekufambisa, psychosis, kushaya kwepvo, kukanganisa, coma, nekufa.
Kana zviratidzo zveutachiona zvichiitika, dzinogona kuramba dzichingogara kwenguva yakareba kunyange mushure mekubudirira kurapwa.
Lithium ichachenesa purogiramu yacho zvishoma nezvishoma muurudzi urwu rwehutano kudarika mumutambo wakaoma. Kana akabatwa pakarepo, gastric rinopisa (mudumbu kupomba) rinogona kuratidzwa.
Kana zviratidzo zvikaonekwa kare, kuderedza kuyerwa kwe lithiamu kana kumira zvachose kungave kurapa kwakakwana, kuwedzerazve muyero wakaderera kana zvichifanira.
Kana zvisina kudaro, ruzhinji rwezvirwere zve dialysis dzinogona kudikanwa kubvisa lithiamu yakawandisa kubva mumutano wevarwere. Muzviitiko zvose, mvura inopisa inogona kupiwa.
Acute on Chronic
Izvi zvinoitika apo murwere anoramba achitora lithium accident kana kuti nemaune anotora chikwata chapamusoro kupfuura chinorayirwa. Nemhaka yekuti hutano hwakanaka uye huwandu hunotyisa hwe lithiamu muropa rakati rava pedo, chiwedzero chinowedzera chinokonzerwa nehutachiona husingaperi hachifaniri kunge chakakwirira kwazvo.
Zviratidzo zvechiitiko ichi zvinosanganisira zvose zviratidzo zvepachiratidzo zviratidzo zvehutachiona uye zviratidzo zvakasimba zvekusagadzikana kwenguva refu. Inonvenous fluid uye nzira ye dialysis inowanzoratidzwa, pamwe chete nezvimwe zvirwere zvinogona kusanganisira zvinodhaka zvekunyunyutira kana kuti kugadzirisa kukanganisa.
Zvakanyanya pane zvisingaperi zvinonzi lithium inxicity inofungidzirwa kuti ndiyo inonyanya kukura, uye ine simba rakakosha remigumisiro yenguva refu.
Outlook for Recover
Vanhu vazhinji vanopora kubva ku lithiamu inxicity pasina zvinetso. Inenge 10 kubva muzana yevaya vane shungu yakaoma inogona kuva nezvinetso zvekugara kwenguva refu, izvo zvinowanzoitika mumamiriro ezvinhu akaoma pamusoro pekugara kwenguva refu inonzi lithium. Pakati pezvinetso izvi, zvinetso zvinowanzova nehutachiona, asi utachiona, itsvo, parathyroid, nemoyo zvinogona kuchinjwa.
> Sources:
> Lithium Inotsanangura Mashoko. Drugs.com . Apr 2007.
> Medline Plus. Lithium Toxicity. National Institutes of Health . 21 Jan 2010.
> Timmer, RT, uye Sands, JM. Lithium Intoxication. Nyaya yeAmerican Society yeNefrology. 10.3 (1999): 666-674.
> Lee, DC, et al. Lithium Toxicity. Medscape Reference . 18 Nov 2010.