Doro Rinodzivisa Kuumbwa kweOsteoblasts
Pamusoro pemigumisiro yese yenguva refu yekudhakwa kunwa doro, zvichida iyo isingazivikanwi ndechokuti kunwa kwakanyanyisa kunogona kukanganisa sei mashesi mumuviri.
Kutsvakurudza kwakaratidza kuti kusingaperi uye doro rinodhaka kushandiswa kunogona kuita kuti kuderera kwemafupa kuwedzere, kuwedzera kuputsika uye kunonoka mukurapa kwezviputi, asi kutsvakurudza kuduku kwakaitwa pamusana pekudhakwa kwewaini pane hutsva hutsva.
Kubudirira uye basa reosteoblasts, masero matsva emasopa, ari pangozi chaiyo yekudhakwa kunokonzera doro, izvo zvinogona kukonzera kuderedza mapfupa ekugadzirisa uye pasi pfupa mashoma.
Vatsvakurudzi veOmaha Veterans Affairs Medical Center vakawana kuti kusingaperi uye kunwisa kunogona kudzivisa kuumbwa kweosteoblasts.
Doro Inokanganisa Kugadzirisa Kwemapfupa
"Kuchengetwa kwemapfupa ane utano muvanhu vakuru vanowanikwa kuburikidza nekugadzirisa kunonzi 'bone remodeling,' akadaro Dennis A. Chakkalakal, nyanzvi yezvekutsvakurudza paOmaha Veterans Affairs Medical Center, purofesa ari muDhipatimendi revhivhi muCreighton University, uye munyori wega chekuongorora. "Pane chero nguva ipi zvayo munguva yehupenyu hwevanhu vakuru, uye mumativi akasiyana-siyana emasaga, zvikamu zviduku zve" bone rekare "zvinobviswa nemasero anonzi 'osteoclasts,' uye pfupa idzva rinoumbwa nemasero anonzi 'osteoblasts.' Mumunhu ane hutano, mabasa maviri aya akaenzana kuitira kuti pasave nekushaya kurasika kwemapfupa. "
Zvisinei, Chakkalakal yakarondedzera kuti kunwa kusingaperi uye kunetseka kunogona kuvhiringidza chikamu nekudzivisa hutsva mapfupa.
"Chinhu chisina chinhu chinogadzirwa nemaitiro ezvisikwa-kutora basa hazvina kukodzera kuzadzwa nefupa rakangobva kuumbwa," akadaro Chakkalakal. "Izvi zvinopfuurira pane dzimwe nzvimbo dzemazamu panguva yekugadzirisa inotevera.
Kuwedzerwa kwechiitiko ichi panguva dzakasiyana-siyana kugadzirisa zvinhu zvinoratidzika sehutachiona hunogona kurasika pamakore mashomanene. "
Kuwedzera Kuputika Kungozi
Chinhu chinokosha chekudzidza kweOmaha chinosanganisira:
- "Doro-inokonzerwa nehosha yemafupa" rinoreva migumisiro miviri yekugara kwenguva refu kudhakwa : kurasikirwa kwefupa (inozivikanwawo osteopenia), izvo zvinoita kuti kuwedzere kuparara kwekuparara; uye kukwana mapfupa ekugadzirisa.
- Doro-inokonzerwa osteopenia yakasiyana ne-post-menopausal osteoporosis uye isashandise osteoporosis.
- Vanhu, zvipfuwo uye sero-tsika zvidzidzo zvinoratidza kuti doro rine zvinokonzera zvinokonzerwa nebasa re osteoblast inoderedzwa newaini.
- Doro rinogona kudzivisa kufanana kwechibvumirano chisina kumira, icho chinovhiringidza kuporesa kuporesa.
- Dorosi inokonzerwa nekurasikirwa kwemafu inobatanidza nekusaipa kwechechi simba mukati mefupa.
Doro Rinokanganisa Osteoblast Basa
"Kuungana pamwe chete, uchapupu hunoti kune tsvina inowanzobatanidza pamwe chete nematambudziko asina kukodzera, akadai sekurasikirwa kwepfupa uye kusakosha mapfupa ekuporesa, uye kushandiswa kusingaperi kwewaini ," Chakkalakal akati.
"Muzviitiko izvi zviviri, doro rinowedzera kukanganisa maitiro osteoblast, nokudaro kubvisa mapfupa mapfupa matsva anodiwa mune zvose zviripo mapfupa ekugadzirisa uye kuporesa kuporesa," akadaro.
"Tinoda zvidzidzo zvemangwana zvinotarisa nzira dzema molecular iyo inodhaka inopesana nehutachiona hwehutachiona.Tinodawo kunyatsoongorora zvinokonzerwa nezvimwe zvinhu zvakadai sekushaya zvokudya zvinovaka muviri, kusvuta uye kusagadzikana kwepanyama sezvakunoita zvidzidzo zvishomanana izvo zvinoongorora migumisiro ye zvinhu izvi. "
"Pakupedzisira, isu tinoda zvidzidzo zvakajeka, zvakanyatsogadziriswa kugadzirisa kukanganisa kwezera-uye zvepabonde pamigumisiro yekuenzanisa uye kudhakwa kudhakwa doro," Chakkalakal akati.
Kuzvidzivirira Kunakisisa Kwazvo Nezvakaitwa Fractures
"Kudzokorora kunosimbisa kukosha kwokurega doro rinoshandiswa nevarwere - doro kana kuti teetotalers - nemakumbo uye avo vangada kunwa panguva yekugadzirisa kwavo," akadaro VA Research Career Scientist Terrence M.
Donohue, Jr.
Sources:
Chakkalakal, DA. "Doro-Yakaita Kuti Bone Irambe Yakapera uye Isina Kugadzikana Kwefupa." Kunwa doro: Kuongorora uye Kuongororwa Ongororo December 2005