Vakadzi vazhinji vari kuita chirongwa cheEcstasy vacharega pakarepo pavanoona kuti vane pamuviri. Asi, zvakadini nemwana wavo asati aberekwa vasati vawana?
Ko Ecstasy (MDMA) inogona kukanganisa fetus mumatunhu ekutanga ekubudirira? Kutsvakurudza kwakabatanidza Ecstasy kushandiswa mumutatu wechitatu wemimba yekuzvitakura pakudzidza kusimba uye neurobiological change.
Zvakadini neEcstasy exposure mumutambo wekutanga wekuita pamuviri?
Kuti uwane, vatsvakurudzi veRush-Presbyterian-St. Chiremba chaRuka Chipatara muChicago akadzidza mazuva makumi mapfumbamwe-makumi mapfumbamwe emapundu maitiro akaiswa pachena kuEcstasy munguva inofananidzwa nekutatu kwekutanga kwehutumbi hwevanhu.
Dr. Jack W. Lipton uye avo vakashanda vakarova rwizi masere ane mimba zuva nezuva ne MDMA kubva pazuva 14 kusvika pazuva 20 yekuzvitakura, nguva inotarisana nemwedzi mitatu yekutanga yekukura kwevanhu. Masayendisiti akapinza saline kaviri zuva rega rega panguva imwechete kune imwe humwe rats rudzvinyiriri rwekudzivirira.
Vatsvakurudzi vakabva vatsvaga hutano hwehuputi dzemakumbo emakumbo pavakanga vemazuva makumi maviri nemaviri, izvo zvakaenzana nemwana wemakore maviri kusvika kumatanhatu.
Kuchinja Kwoutsinye Kunochengetedzwa
"Chiitiko chedu chinotyisa ndechekuti mazuva makumi maviri nemaviri ekupedzisira ecstasy-akazaruka aine 502-peresenti yekuwedzera muwandu hweiyo dopamine neuron fibers mumakona ekutanga akasiyana nemhuka dzinodzora," akadaro Dr. Lipton.
"Kusagadzikana kana kuwandisa kakawandisa mumakona ekutanga kunogona kukonzera kugadzirisa kujekesa ikoko, zvichida zvichiguma nemafambiro asina kunaka.
"Dopamine ikemikari yeuropi inotakura kana kutumira mameseji pakati pemasero emagetsi. Inobatanidzwa mumhando dzakasiyana-siyana dzinokurudzira, dzakadai sokudya, zvepabonde, nekushandisa zvinodhaka.
Iyo cortex yakatarisana inokosha pakuronga, kutora pfungwa, nekucherechedza. "
Kusiyana Kwepakati Mukudzvinyirirwa?
Chidzidzo chacho chakaratidzawo maduku asi asi akafanana mune dopamine fibers muuropi nzvimbo inobatanidzwa mukudzivirira uye mubairo uye nzvimbo yepamusoro yezviito zvekupa mubayiro zvinokurudzira, nucleus accumbens.
"Zviratidzo zvehutachiona zvakasununguka zvakare zvakaratidza kuderedza kuderera mune dopamine metabolism muhutano hwehutano hunoita basa rinokosha mukubhadhara, kusagadzikana, kudzidzira, uye kufamba.Paivawo nekuderedzwa kwe serotonin metabolism Serotonin zvakare chimiro chepfungwa chinobatsira kudzora mafungiro, kurara, uye chido, "Lipton akadaro. "Zvinofadza kuti kuderedzwa kwe dopamine uye serotonin metabolism iyo yakaonekwa mumusikisi yakawanda yakaonekwa munhurume, asi kwete vakadzi, pup dzinoratidza kusawirirana kwepabonde mukunetseka kune zvimwe zvinokonzerwa neEcstasy."
Kuchinja Kwounhu Kuonekwa
Chidzidzo cheChicago chakaratidzawo kuchinja kwehutano mumhuka.
"Apo mazamu e-Ecstasy-akapfigwa akaiswa munzvimbo itsva kunze kwevadziviriri vavo, ivo vakapedza nguva yakawanda nguva vachiongorora, vachiratidza kuti havana kugadzirisa nyore nyore kune mamiriro matsva semhuka dzinodzora," vakanyori vakadaro.
"Zvatinowana zvinoratidza kuti kuisa rats kune Ecstasy panguva yekukura kwepabonde kunobatana nekutanga kwevatatu muvanhu kunogona kuguma nekuchinja kwehupenyu muhupi hwemakemikari uye mufambiro," akadaro Dr. Lipton.
"Zvatinowana zvinoratidzawo kuti kujekesa kweMDC kunogona kukonzera kusagadzikana kana kukanganisa kutarisirwa kana kudzidza.Umwe hutsvakurudzo hunodiwa kuti udzidze zvakawanda pamusoro pemigumisiro yekusununguka kwepabonde kune ichi chinodhaka."
Kudzidza, kubhadharwa mune chikamu neNational Institute on Drug Abuse.
Sources:
Koprich, JB, uye al. "Kuberekera pamuviri 3.4-methylenedioxymethamphetamine (ecstasy) kunochinja maitiro ekuongorora, kunoderedza monoamine metabolism, uye kunowedzera forebrain tyrosine hydroxylase fiber kuwanda kwevana rats." Neurotoxicology uye Teratology October 2003