Kusarudzwa kweSerotonin Reuptake Inhibitors (SSRIs) kushanda sei
Reuptake chinhu chinokosha chemishonga kunzwisisa kana iwe une borderline person disorder (BPD) kana chimwe chinetso cheutano hwepfungwa. Sei? Nokuti mishonga yakawanda inoshandiswa pakurapa zvirwere zvehutano hwepfungwa inoshanda kuburikidza nekuchinja dzimwe nyanzvi dzemhando dzepamusoro muuropi. Reuptake chikamu chikuru chekuita izvi.
Neurotransmitters ndiwo makemikari anopihwa anopa nzira yekutumira mitsara yakabudiswa nemasero emasero (neurons) kune synaps es (nzvimbo dziri pakati pemasero) kubva pane imwe sero cell kusvika kune imwe.
Reuptake ndizvo zvinoitika mushure mekunge chiratidzo chichiparidzirwa: The neurotransmitter, "basa" rayo rapera, rinodzoserwa zvakare muchikamu chekare chakasunungurwa.
Sei Kuchengeta Kuchikosha Mukurapa kweBPD Kuora Mwoyo?
Kushungurudzika muBPD nezvimwe zvirwere zvehutano hwepfungwa zvinosanganiswa nehuwandu hwehutano hwemamwe mapikisi emakemikari, kusanganisira serotonin, dopamine, uye norepinephrine.
Kana iwe uine BPD uye uri kutora mishonga yekurapa kuora mwoyo (mune mamwe mazwi, anodzvinyirira), unogona kutora serotonin reuptake inhibitor kana SSRI inosarudza . Izvo zvinowanzozivikanwa zvinorambidzwa zvinodhaka, SSRIs inowanzoshandiswa kurapa vanhu vane BPD nekuderedza zviratidzo zvekuenzanisa kuora mwoyo zvakanyanya.
SSRI inowedzera huwandu hweeurotransmitter serotonin muuropi, sezvamunoziva zvino, kuderedza kushandiswa kwayo zvakare mumasero akaiparadzira. Somugumisiro, zvakakwirira-kudarika-zvese zvema serotonin zvakasara kuti zvipararire muuropi.
Kuwedzerwa huwandu hweSerotonin muuropi hunoonekwa huchibatsira masero europi achitaurirana, izvo zvinobatsira kubatsira kusimudza kuora mwoyo nekuvandudza mafungiro. Serotonin yave ichinzi muviri wemasikirwo "kunzwa-akanaka" nokuti inounza pfungwa yekugara zvakanaka.
Sezvaunogona kuona, SSRIs haibatsiri muviri kuti utange serotonin yakawanda.
Pane kudaro, vanobatsira mutumbi kupararira zvimwe serotonin zvazviri.
Mienzaniso yeSSRIs
Heino mazita emaSRRIs anowanikwa kunechiremba wako kuti anyore:
- Citalopram (Celexa)
- Escitalopram (Lexapro)
- Fluoxetine (Prozac, Sarafem)
- Fluvoxamine (Luvox)
- Paroxetine (Paxil, Paxil XR, Pexeva)
- Sertraline (Zoloft)
Shoko rekuyeverwa kweSerotonin Syndrome
Nzira ye reuptake inobatsirawo mune izvi zvisingaiti asi zvinotyisa, izvo zvinoitika apo munhu anotora mishonga miviri inowedzera nhengo ye serotonin mumuviri. Izvi zvinogona kukonzera nengozi dzakakwirira senotonin mazinga muuropi.
Mishonga yausingafaniri kutora pamwechete inosanganisira:
- Anodzvinyirira, kusanganisira SSRIs
- Mamwe marwadzo kana mishonga yemusoro
- Mishonga inowedzera wechechi yaJohn John
Zviratidzo nezviratidzo zve serotonin syndrome zvinosanganisira:
- Rapid moyo rate
- Kufunganya
- Kushungurudzika
- Kusina kubatana
- Kusanganiswa
- Sweating
- Kutuka
- Kusagadzikana
Kana uine chimwe chezviratidzo izvi kana zviratidzo, enda kuchipatara rubatsiro pakarepo.
Serotonin syndrome inowanzoitika apo iwe unotanga kutora mishonga inokurudzira serotonin kana iwe paunowedzera chirwere.
Serotonin syndrome haigoni, zvikurukuru nokuti vanachiremba vanonyatsochenjerera nezvekunyorera mishonga inogona kuitisa. Kunyange zvakadaro, nokuti chirwere ichi chinotyisa, FDA yakabvunza venzi vemhando idzi dzemishonga kuti vaise mabhuku ekunyevera kune avo vanogona kukubvumirai kune ngozi iyi.
Sources:
"Sei SSRI inoshanda." Healthline.com (2013).
"Kuora mwoyo (chikuru kuora mwoyo): sarotonin reuptake inhibitors (SSRIs)." Mayo Clinic (2013).
"Serotonin Syndrome." US National Library of Medicine. MedlinePlus (2016).