Zviratidzo zveSerotonin Yakawanda
Zvirwere zvinodhaka zvinonzi serotonin reuptake inhibitors (SSRIs) zvinoshandiswa sevashandi vokutanga mukurapa chirwere chinotyisa uye zvimwe zvinetso zvekuzvidya mwoyo . SSRI inowedzera hutano hwe serotonin muuropi, zvichiita kuti kuderedzwa kunetseka uye kudzivirirwa kwekutya kwekutya. Munhu wacho anganzwa akaneta kubva pakuwedzera kweserotonin, ine zvishoma zvishoma uye shomanana kurwisa.
Asi, kana maitiro e serotonin akakura zvikuru, chirwere chakakomba chinonzi serotonin syndrome chingaguma.
Uropi hwemunhu hunotendwa kuti hushanda mune zvakakomberedzwa mumakemikari nzvimbo kuburikidza nemhando dzakasiyana dzeeuron neurotransmitters . Neurons ndiwo masero europi, achiverenga mumabhiriyoni, anokwanisa kukurumidza kutaura kune mumwe nomumwe kuburikidza nemakemikari anonzi neurotransmitters. Serotonin ndeimwe yemakemikari vatumwa. Inobatsira pakugadzirisa kufunganya, mafungiro, kurara, kudya, uye zvepabonde. Serotonin inoburitswawo mumigwagwa yekudya, ichiita basa mukudya uye dzimwe nzira dzomuviri.
Overview
Serotonin syndrome, kana serotonin chepfu, isingawaniki chinokonzerwa nenjodzi yakakwirira ye serotonin muuropi. Inogona kunge inogona kutyisa upenyu. Inowanzokonzerwa nekubatanidza mishonga miviri kana kupfuura iyo inobata maitiro e serotonin muuropi.
SSRIs, SNRIs , tricyclic antidepressants , MAOIs , uye triptans zvikamu zvose zvemishonga izvo zvave zvichibatanidzwa mukugadzirwa kweserotonin syndrome. Izvi zvinowanzotarisirwa kuti zvirape kushushikana nekuzvidya mwoyo, kusanganisira panic disorder.
Zviratidzo nezviratidzo
Zviratidzo nezviratidzo zve serotonin syndrome zvinosanganisira:
- Kusanganiswa
- Kurasikirwa kwekubatana
- Tsvina yakasimba
- Kusagadzikana
- Hallucinations
- Kunetseka kukuru
- Kusiyana kwepfungwa muropa
- Heart palpitations
- Nausea, kurutsa, chirwere
- Fever
- Kugumburwa
- Coma
Mishonga
Sezvo serotonin syndrome inogona kunge inogona kutyisa upenyu, kurapwa kwekukurumidzira kunokosha. Kurapa kunotanga nekuregera kwemishonga inokonzera. Izvozvo zvinokonzerwa neserotonin syndrome zvinowanzopedza maawa makumi maviri nemasere nemaawa makumi maviri nemashanu mushure mekunge mishonga inobata serotonin inomiswa. Zvisinei, zvimwe zvezvinetso zvakadai sedrium uye kusagadzikana kwemaitiro emwoyo, kukonzerwa kweropa, kutonhorera uye mamwe mabasa ehurumende yekutonga inogona kuramba ichireba. Nzira dzokutsigira uye kupindira mune zvigaro zvechipatara zvinogona kudiwa uye zvinosanganisira:
Kuyeresa kwomwoyo uye kuvharirwa kweropa: Mishonga yekuderedza kuwanda kwemwoyo uye kuwedzerwa kweropa (kureva, esmolol kana nitroprusside) inogona kudiwa. Mishonga inogonawo kupiwa kana kuwedzerwa kweropa kwakanyanya.
Kudzora kwekushisa: Zvingave zvakafanira kurapa zviratidzo zvefivha nemavheekete ekufema uye vateereri vemubhedha.
Sedation: Benzodiazepines inogona kushandiswa kubatsira kubvisa musidhi rigidity uye kushungurudzika kwakanyanya.
Kuwedzerwa kwemvura : Inotvenous fluid inogona kudiwa kuti igadzirise zvinodiwa zve hydration.
Cyproheptadine: Dzimwe nguva inoshandiswa kudzivirira kubudisa serotonin mumuviri. Yakaratidza kubudirira mukuderedza kuoma kwezviratidzo zvinosanganisira serotonin syndrome.
Kudzivirira
- Udza chiremba wako nezvemishonga yose yauri kutora panguva ino. Izvi zvinosanganisira mishonga yemishonga, mishonga-in-counter, uye zvinowedzera.
- Kana iwe uri kutora mishonga inobata maitiro e-serotonin, taura nachiremba wako pamusoro pezvipingamupinyi zvako zvekuvandudza serotonin syndrome.
- Tsvaka rubatsiro rwekurapwa nokukurumidza kana uri kutora mishonga inobata maitiro e serotonin uye iwe unokura chero zviratidzo zve serotonin syndrome.
Sources:
> Prator, Bettina C. "Serotonin Syndrome." Nyaya yeNeuroscience Nursing . April 2006. 38 (2): 102-105.
> US Food and Drug Administration. Zvichida Upenyu-Hunopisa Serotonin Syndrome neKushandiswa Kwakasiyana kweSSSRIs kana SNRIs uye Triptan Mishonga. July 19, 2006.