Bipolar mood stabilizers library
Topamax (generic topiramate) inonzi antiticonvulsant mishonga inogamuchirwa neU.S. Food and Drug Administration (FDA) iyo inoshandiswa mukurapa kuora mwoyo uye migraine musoro. Kunyange zvazvo Topamax yave ichiri uye ichienderera mberi ichidzidzwa kuti ishandiswe mukurapa bipolar disorder , haisi FDA inobvumirwa kuti ishandiswe. Zvisinei, vanachiremba vazhinji vanopa Topamax off-label ye bipolar disorder.
Zvidzidzo zviviri zvekuchiremba zvekuchipatara zvakagamuchirwa neavo zvidzidzo zvekare, zvichiona kuti Topamax yaibatsira bipolar disorder kana yakashandiswa sechiwedzera kune mamwe mafungiro emagariro asi kwete kunyanya kubudirira kana ishandiswa yoga.
Topamax inowanzosvibiswa se Topomax.
Topamax inouya mahwendefa uye mumapirisa ayo angasvinudzwa uye anosaswa pane zvokudya zvinyoro zvakadai sepudding, yogurt, ice cream, uye zvimwe zvokudya zvisingatsvaki kucheka. Kana ukashandisa Topamax kusasa makutu, iwe unofanirwa kudya zvose zvinoshandiswa zvekudya kamwechete; usazvichengetera zvakare.
Zviyeuchidzo Zvikuru pamusoro peTaramaamax
- Metabolic Acidosis. Kushandiswa kweTramaamax kunobatanidzwa nechiitiko ichi, umo ropa rinova rakaoma. Pane njodzi yakakwirira yekutengesa metabolic acidosis muzvirwere zvepachiviri 15 uye pasi. Zviratidzo zvinopfuurira kufema (hyperventilation), kuneta, kuramba kudya, uye kunyura. Izvi zvinogona kuva zvakakomba kana zvisina kutarisirwa. Itaiti yakagamuchirwa yeTopamax inokurudzira kuenzanisa ropa acidity paanotanga kurapa uye kuongorora nguva nenguva.
- Glaucoma. A syndrome ine ruzivo rwakanyanya rwekuona zviri mberi (myopia) inosangana nedambudziko reziso rinonzi secondary angle yekuvhara glaucoma rakaitika kune varwere vachishandisa Topamax. Zviratidzo zvinowanzoonekwa mukati memwedzi wekutangira Topamax mishonga uye inosanganisira kusvibiswa kwekuona kwemaonero, kurwadziwa kweziso, uye dzimwe nguva kubwinya kana kuwedzera vana. Kana uchinge uine chimwe chezviratidzo izvi, taura iwe unorayira chiremba pakarepo. Kana chiremba chinoratidzika chisingawanikwi, taura ne ophthalmologist.
- Kupera Kwakaipira uye Fever. Izvi zvinonyanya kuzivikanwa muvana, uye varwere vanofanira kuongororwa nekuda kwezviratidzo izvi, kunyanya mukupisa. Nemhaka yokuti mimwe miviri yakatemwa uye inopfuura-iyo-mishonga inogona kuita kuti munhu awedzere kutonhora kupisa, edza kuti chiremba wako uye wemhizha vanoziva mishonga yose murwere ari kutora.
- Usarega kutora Topamax pakarepo. Ikoko kune ngozi yakawedzerwa yekugumburwa kana izvi zvaitwa.
- Kidyo Matombo. Ikoko kune ngozi yakawedzerwa yekuve nekugadzira mazinyo eminwe pakutora Topamax. Iva nechokwadi chokuti unwe mvura zhinji.
- Renal Impairment. Sezvo Topamax yakasunungurwa kubva mumuviri kuburikidza neitsvo, kuyerwa kunogona kudiwa kugadziriswa nevarwere vane urombo hwekuora, kunyanya kune avo vane makore makumi matanhatu nemaviri kana kupfuura.
Topamax Drug Interactions
- Zvimwe Anticonvulsants. Mumakiriniki ekuedzwa, kubatanidza Tegretol (carbamazepine) neTramaamax kwakaguma nekuderera kwe40% muhuwandu hweTeammax huripo. Ne Lamictal (lamotrigine), uwandu hweTramaamax hwakawedzera 15%, uye neDepakote (valproic acid), zvose zvinodhaka 'zvakanyanya zvakaderedza 11-14%. Zvisinei, Topamax neDepakote pamwe chete zvinokonzera njodzi yehutano hunonzi hyperammonemic encephalopathy. Zviratidzo zviri kuchinja kwakanyanya muhutano hwekuziva uye / kana kugadzirisa basa nekunyengera kana kurutsa.
- Zvipfeko zveMuromo. Pane njodzi yekudzivirira kubata pamuviri nekudzivirira kubuda ropa pakutora Topamax nemishonga yekudzivirira ine esrogen.
Kune humwe humwe hutano huripo hwekushandisa kwemishonga. Verenga kuisa ruzivo rwakanyatsonaka uye zvakare, iva nechokwadi chokuti chiremba wako uye wemhizimisi vanoziva mishonga yose, zvose zvakatemerwa uye pamusoro-the-counter, zvauri kutora.
Topamax uye Kubata / Breast-Feeding
Zvidzidzo zvezvipfuwo zvakaratidza dambudziko guru kune fetus kubva kuThemaamax, uye kuvanhu, kune ngozi yakawedzerwa yakawanda yezvakaberekwa zvinokonzerwa neyekunyora kwemuromo. Zvakakosha kubvunzurudza chiremba wako kana iwe uri pamuviri kana kuronga kuva nepamuviri.
Topamax inofanira kushandiswa panguva yekuzvitakura chete kana iyo inobatsira inowedzera kukanganisa kwocheche mwana asati aberekwa. Kunyange zvazvo pasina dzidzo dzakarongedzwa pamusoro pekudzivirirwa kweTramaama mumukaka, uchapupu hunoratidza kuti hwakavanzwa zvakanyanyisa, uye zvakare, kuyera zvinobatsira uye njodzi zvakanyatsonaka.
Maitiro Anowirirana Nezvakawanda zveTopamax uye Topiramate
Nyaya inowanzozivikanwa yechirwere cheTramaMax inonzi paresthesia kana kumira kwemagumo. Matambudziko anowanzoita kuti vanhu vabve kunze kwekuongororwa kwekliniki vaiva kurara uye kuneta. Mishumo yekuneta kunowedzera papamusoro madheji. Sezvo kune chikonzero chekuzorora, kupesana, uye kuoma kuisa pfungwa, usingafambisi kana kushandisa mishonga kusvikira iwe uchiziva kuti unoita sei kune iyi mishonga.
Mimwe migumisiro yakazara inosanganisira:
- Kufirwa kwechido
- Kuonda
- Matambudziko ane chiyeuchidzo, kuisa pfungwa kana kutarisa
- Muvana, kumusoro kupemha chirwere
Topamax uye Kurasikirwa Kwekurema
Zvakawanda zvave zvichiitwa pamusoro pekukwanisa kuperevedza Topamax. Mumakiriniki ekuedzwa, kuyerwa kunorema kwakaitika kusvika 21% yezvidzidzo, kazhinji zvishoma pane izvozvi, uye zvakange zvichitarisira, uye vanhu vazhinji vanorema uwandu hwe 400mg pazuva. Sezvo njodzi yemigumisiro inowedzera nehana yakakwirira, munhu mumwe nomumwe anofanira kuongorora mhinduro yake kumushonga.
> Sources:
Kushner, SF, Khan, A., Lane, R., Olson, WH (2006). "Topiramate Monotherapy muMutungamiri weAacute Mania: Zvikamu zveNzvimbo Dzaviri Dzisina Mberi-Miedzo Inodzorwa." http://www.ncbi.nlm.nih.gov/entrez/...&list_uids=16411977.
McIntyre, RS, Riccardelli, R., Binder, C., Kusumakar, V. (2005). "Shanduro Yakazarura Inobatanidza Topiramate Mukurapa Kwechigadzikana Bipolar Disorder." http: //www.ncbi.nlm.nih.gov/entrez /...& list_uids = 16086539 ....
Medline Plus Medical Encyclopedia. (2005). "Glaucoma." https://medlineplus.gov/ency/article/001620.htm.
Medline Plus Medical Encyclopedia. (2006). "Metabolic Acidosis." https://medlineplus.gov/ency/article/000335.htm.
US Food and Drug Administration. (2005). "FDA Inobvumirwa Kunyora Musoro Dated 6/29/05 yeTopamax® (topiramate) Matethe uye Topamax® (Topiramate Capsules) Fukisa Makapuisi."