Genesisi Ndicho Chimwe Chete OCD Puzzle
Neine gome revanhu iro rakazove rakarongedzwa, kutsvaga kuri kwemajeni aya anoita kuti isu tive nehutano, kusanganisira kuvhunduka-kukanganisa chirwere (OCD). Kunyange zvazvo zvakajeka kuti OCD ine mazamu, hazvisi pachena kuti zvipi zvingave zvakakosha uye pasi pemamiriro api.
Zvirwere uye Kurwara: A Primer Brief
Usati wataurirana kana pane mazita ekuberekwa kweOCD, regai tiongororore mamwe mazano ezve genetic uye kuti anoenderana sei nehosha.
Genesheni inoshanda senhengo yemuviri yekuita mapuroteni akasiyana. Aya mapurotini anoshandiswa kugadzira nhamba yakawanda yemasukisi uye biochemicals. Zvinofadza kuti vanhu vakasiyana vanogona kunge vane zvinyorwa zvakasiyana zvegomu rakapiwa. Iyi shanduro dzakasiyana dzimwe nguva dzinonzi alleles.
Kunyange zvazvo dzimwe zvirwere zvakadai se cystic fibrosis zvinofungidzirwa kuti zvinokonzerwa nejena rimwe, zvirwere zvizhinji, kusanganisira zvirwere zvepfungwa seOCD, zvinofungidzirwa kuti zvinokonzerwa nekubatanidzwa kwemajini akawanda akasiyana. Muzviitiko izvi, kutambudzwa kwako kune chirwere chinopiwa kunobva kune zvakasiyana-siyana kana zvinyorwa zvemajini mawakagara nhaka kubva kuvabereki vako uye mune zvakasanganiswa.
Zvakatipoteredza Zvinotamba Basa Guru Mukurwara Kukura
Zvisinei, zvakakosha kuziva kuti mamiriro ezvinhu ane simba rakasimba kwazvo pane kana chimiro chinokonzerwa nehutachiona chinokwanisa kuzviratidza mumamiriro ehutano. Semuenzaniso, munhu ane zvipembenene zvinokonzerwa nemukenza wemapapu anogona kungoita chirwere ichi kana achitsvuta fodya kana kuti akabatwa nekusvibiswa kwemhepo yakasvibirira.
Mune imwe nguva, munhu anenge achinetseka kuora mwoyo angasazomboora mwoyo kana asingambotarisana zvakanyanya zvakanyanya kudzvinyirira.
Kunyangwe tichiwanzozvinzwa pamusoro pe "chimiro kana kuzvisimudzira" nharo, nyanzvi dzakawanda zvino dzinoziva kuti ndiko kubatana pakati pemagetsi edu uye zvakatipoteredza zvinosarudza kana tinokura chirwere.
Zvechokwadi, zvinowanzotaurwa kuti apo majini edu "anotakura bhuti," ndiyo mamiriro ezvinhu "anokonzera mutsara."
The Genetics of OCD
Kutsvakurudza kushandiswa kwemajaya akafanana uye hama dzevanhu vane OCD dzinoratidza kuti chinhu chinonyanya kukosha muhutano hwemunhu wekuvandudza OCD inonzi genetic, ine ngozi yakasara inotsanangurwa nemhepo. Zvichipa izvi, vatsvakurudzi vanga vachitsvaga majee ega anokonzera njodzi yekuvandudza OCD. Kunyange apo iyo isingaoneki seye "OCD gene", pane humwe humwe uchapupu hwekuti dzimwe shanduro kana alleles yemamwe magenhi anokwanisa kuratidzira kukanganisa kukuru.
Semuenzaniso, kune humwe humwe hupupuriro hwekutanga hwokuti kune dzimwe shanduro kana alleles yemagenera ekudzora kushandiswa kwe serotonin (neurochemical iyo inogona kukosha kuOCD), uropi-yakagadzirirwa neurotrophic factor (ikemikari inoita basa guru pakutevedzera kukura kwe ubongo) uye glutamate (imwe yeurourochemical muuropi iyo inogona kukosha kuOCD) inogona kuratidzira rudzi rwekushungurudzika pakuvaka OCD. Izvozvo zvakati, hazvirevi pachena kuti mazamu aya anokonzera kukura kweOCD, uye kune zvakawanda zvekutsvakurudza izvo zvichiri kudiwa kuitwa.
Genetic Vulnerability Inoreva Zvishoma Zvisina Njodzi
Mukuwedzera, zvakakosha kuchengeta mupfungwa kuti idzi (nezvimwe, sezvisati dzisati dzamboonekwa) maitiro ehutachiona angangodaro anoshanda pasi pemamiriro ezvinhu akanaka.
Semuenzaniso, OCD inobatanidza nehutano hwepabonde, sekuwana kuwandisa zvakanyanya paunenge uri nepamuviri uye kushanda zvakaoma, pamwe chete nekumanikidzwa kwehupenyu, zvakadai sekushushikana mupfungwa kana kushungurudzwa. Sezvo zvakadaro, mumwe munhu angave asina kukura OCD kunze kwekuti vane kodzero yekutengesa genetic pasi pezvakarurama (kana zvakaipa, zvichida) mamiriro ezvinhu.
OCD chirwere chakaoma kwazvo. Hazvigoneki kuti imwe geni iri kunze kwevanenge makumi matatu nemakumi matatu vatinenge tinazvo inogona kuva nechinangwa chekugadzirisa kushungurudzwa kwakaoma uye kumanikidzirwa kunofananidzwa neOCD. Zvinonyanya kuitika kuti OCD inokonzerwa nejeri dzakasiyana-siyana dzakabatana kuti dziwedzere kukura.
Studies of the genetics ye OCD ikozvino inotarisa maitiro ezvisikwa zvinogona kutsanangura maitiro akasiyana eOCD echiratidzo subtypes chiripo. Kutsvakurudza kwakadaro kunogona kubatsira pakugadzira kurapwa kunokwanisa kutarisa zviratidzo zvakananga nekubudirira zvakanyanya kudarika ikozvino zvichibvira.
Sources:
Samuels, JF "Kufambira mberi Kwakaitika muGenetics yeOCD" Nhau dzePist Psychiatry 2009 11: 277-82.
http://www.ocdeducationstation.org/ocd-facts/what-causes-ocd