Migumisiro Yechiri, Manyevero, Kubatana
Cymbalta (duloxetine hydrochloride) serotonin-norepinephrine reuptake inhibitor (SNRI) inodzvinyirira. Inotorwa nemuromo sepiritsi kana capsule.
Zviratidzo uye Kushandisa
Cymbalta inoshandiswa pakurapa kukuru kwekuora mwoyo chirwere. Kubudirira kweCymbalta yekushandisa kwenguva refu, kana kupfuura masvondo mapfumbamwe, hakuna kuongororwa zvakarongeka mumakiriniki ekuedzwa.
Inoshandiswawo kune vatungamiri vehutachiona hwepabhesi marwadzo europathic, fibromyalgia, muswere musingaperi uye mapfupa uye zvinokonzera kushungurudzika kwepfungwa.
Contraindications
Cymbalta haifaniri kushandiswa nemumwe munhu akaratidza kunzwisisika kune duloxetine kana chero ipi zvayo yeCymbalta isingashandi. Inofanirawo kushandiswa panguva imwe chete se monoamine oxidase inhibitor (MAOI) inodzvinyirira. Mumakiriniki ekuedzwa, Cymbalta yakabatanidzwa nekuwedzera mydriasis, iyo iri kuwedzera kwevadzidzi veziso, kune varwere vasina kutongororwa nechepamusoro-angle glaucoma uye havafaniri kushandiswa nevarwere vane chirwere ichi.
Precautions
Pakave nemimwe mitsara yekushaya chiropa mune varwere vachishandisa Cymbalta. Yakave ichibatanidzwa nekuwedzera kweropa, saka kushanda kweropa kunofanira kuongororwa mukati mekurapa. Cymbalta inofanira kushandiswa nekuchenjerera kune varwere vane nhoroondo yekushungurudza kana kukanganisa.
Hazvifanirwe kushandiswa kune avo vasina kutongororwa mashoma-angle glaucoma. Inofanira kuregedzwa zvishoma nezvishoma kuti isabvisa kumira kwezviratidzo. Chiitiko neCymbalta mune varwere vane dzimwe zvirwere zvishoma.
Manyevero
Varwere vanofanira kuchengetedzwa zvakanyanya pakuwedzera kuora mwoyo nekuzviuraya, kunyanya pakutanga kwekurapwa kana kana kuchinja kwehutano kuchiitwa.
Varwere vanofanirawo kuongororwa nokuda kwezviratidzo zvakadai sokuzvidya mwoyo, kushungurudzika, kusagadzikana, kutya kwekutya, kusuruvara, kusagadzikana, kuvengana, kusagadzikana, hypomania uye mania. Kana zviratidzo zvakadaro zvakanyanya, zvinoitika kamwe-kamwe kana zvisiri zviratidzo zvaivapo vasati vatanga kurapwa, kufunga kunofanira kupiwa kuchinja murwere kune mumwe mushonga.
Kubatana Kwemishonga
Ruzivo nezvekubatana kwezvinodhaka nguva yakawandisa kupfupisa pano. Ndapota shanyira webhusaiti yeDFA kana utaure nachiremba wako kana mhizha kuti uwane mamwe mashoko akazara.
Carcinogenesis, Mutagenesis, Kuora Kwekubereka
Madzimai echikadzi anowanikwa zvakaenzana ne11 zvakanyanya kukurudzirwa chirwere chevanhu (MRHD), pane kuwedzera kwe hepatocellular adenomas uye carcinomas. Izvo-hazvina maturo chiitiko chaive ka4 MRHD. Kumuvirirwa kwepamuviri kwakanga kusina kuwedzerwa munhurume mice pamakisikiti kusvika ma8 MRHD. Yakanga isiri mutagenic mune zvidzidzo zvakaitwa kana kuti haina kuchinja kubereka.
Kuberekwa uye Lactation
Cymbalta iClass C drug. Hapana dzidzo dzakakwana uye dzinochengetedzwa zvakanaka mumadzimai ane pamuviri, saka duloxetine inofanira kushandiswa panguva yekuzvitakura chete kana kubatsirwa kunobatsira kukonzera ngozi kune fetus.
Migumisiro Yechechi yeCymbalta
Zviitiko zvinowanzovhiringidza zvakanyanya, zvinonzi zvakawandisa kupfuura 5%, zvakange zvichishungurudza, zvakaoma muromo, kuvimbiswa, kuderedza chido, kuneta, kurara, uye kuwedzerwa kutuka.
Zviitiko zvakashata zvinowanzoitika mune zvinenge 2 muzana zvevarwere zvinosanganisira kurara, kushambidzika, kuora muviri, dutu, kudengenyeka , kupisa kunopisa, kuonekwa kwakashata , kusuruvara, kuzvidya mwoyo uye zvepabonde.
Kushandisa Zvinodhaka Nokuderera
Duloxetine haisi chinhu chinodzorwa. Mune zvidzidzo zvemhuka, haina kuratidza bharururate-sekushandisa kushandiswa kwekushandisa. Mukutsvakurudza kwezvinodhaka, hazvina kuratidza kuvimbika-kubudisa mikana mumakonzo. Kunyange zvazvo Cymbalta isina kuongororwa zvakananga mumunhu nekuda kwekushandiswa kwayo, pakanga pasina zviratidzo zvekutsvaga zvinodhaka mumakiriniki.
Dosage uye Administration
Cymbalta inofanira kutarisirwa pamutengo wezuva nezuva we 40-60 mg / zuva.
Kazhinji, ichaparadzaniswa kuva maitiro maviri akatorwa panguva dzakasiyana dzezuva. Hazvifaniri kuitora nechingwa. Hapana humwe uchapupu hwokuti doses rinopfuura 60 mg / zuva rinopa chero mamwe mazano.
Kunobva:
"Nheyo dzekunyora mashoko: Cymbalta (Duloxetine Hydrochloride) - Derayed-Release Capsules for Oral Use." US Food and Drug Administration Website. US Food and Drug Administration. Yakarongedzwa: December 4, 2008. Yakasvika: December 4, 2015.