Migumisiro Yechipfuva, Kuwirirana uye Njodzi
Prozac inonzi antidipressant iyo yakatanga kubudiswa muUnited States kuti iite kushushikana kwema1980. Icho chikamu chekirasi yemishonga inozivikanwa sekusarudza serotonin reuptake inhibitors (SSRIs). Prozac inonyanya kushandiswa kugadzirisa kudengenyeka kukuru, kuvhara-kusagadzikana, uye panic disorder (zvinoshandiswa zvinoshandiswa neU.S. Food and Drug Administration) asiwo dzimwe nguva zvinoshandiswa pane-label kuitira kubata mamwe matambudziko ekuzvidya mwoyo.
Izvo Prozac Inobatsira Nokuzvidya Mwoyo
Mechanism of Action
Sangano re SSRI, Prozac inoshanda nekudzivirira huropi kuti irege kudzorera serotonin chaiyo. Serotonin inobatanidzwa mukugadzirisa mafungiro. Nenzira iyi, Prozac inobatsira uropi kuchengetedza zvakakwana serotonin kuitira kuti uve nemanzwiro ehupenyu hwakanaka, zvichibva pakuvandudzwa kwekukurukurirana pakati pemasero europi.
Kutsvakurudza kunoratidzawo kuti mishonga yakadai seProzac inogona kubatsira sei pamwe nehana yepfungwa. Mune chidzidzo che2008 chakabudiswa muScience, zvakaratidzwa kuti mumakonzo, Prozac akabatsira uropi kupinda mune imwe nyika isina kufema uye yeplastiki, zvichiita zvichiita kuti zvive nyore kuti kurapwa kuve nemigumisiro. Isu tinoziva kuti kubatanidza mishonga yakadai seProzac nehutano hwekutaura hunobudirira mukuzvidya mwoyo, uye chidzidzo ichi chinoratidza chikonzero chingaita nei.
Zvinotinetsa Kufanana Kutora Prozac
Kana ukaona kupindura kwakanaka kwaProzac, unogona kuona kuderera kwezviratidzo zvekuzvidya mwoyo.
Zvichienderana nezviratidzo zvako, iwe unganzwa uchinzwa wakasununguka uye usina kunyanya kuzvidya mwoyo, kunatsiridza muhope uye chido, kufarira muupenyu, kuwedzerwa simba, kuvandudza mano ekufunga, uye kunzwa zvakanyanya kufanana newe pachako zvakare.
Yeuka kuti zvingatora nguva yekuvandudzwa uku kuonekwa-kunyange kusvika masvondo gumi nemaviri mune dzimwe nguva.
Iwe unogonawo kuve nemigumisiro pakutanga pakutanga, saka zvingava zvakaoma kucherechedza kuvandudzwa kusvikira migumisiro yechirwere ichidzikira.
Kushandisa Prozac Kwekuzvidya Mwoyo
Kuwana Chirairo
Prozac inowanzotorwa kuti yakatanga kurapwa kwemashoko ekutambudzika kwekuzvidya mwoyo. Zvisinei, pane zvikamu zvakasiyana-siyana zvinowanikwa mukuwana mishonga. Kazhinji, kuongororwa kwepfungwa yehutano hwepfungwa kunofanira kupiwa usati waudzwa Prozac. Kunyange zvazvo chiremba wemhuri ari kukwanisa kunyora mishonga, chirongwa chacho chiri nani kutariswa nenyanzvi yehutano hwepfungwa iyo inogona kupa mishonga, yakadai sechiremba chepfungwa.
Dosage uye Administration
Prozac inowanzotarisirwa pamushandi wepasi kuti utange, uye zvishoma nezvishoma kuwedzera kusvika 20 mg pazuva. Iyo yakawanda inonzi 80 mg pazuva. Inotorwa semvura kana capsule, uye inofanira kushandiswa sezvinorayirwa. Zvinogona kutora mavhiki mashoma kuti zvigadzirwe kuratidza, saka zvakakosha kusarega kutora Prozac pakarepo kana iwe uchifunga kuti kusashanda. Ingotora mishonga sezvinorayirwa nachiremba wako kana chiremba chepfungwa. Kuchengeta kutonhora kunogona kuva nengozi uye kunokonzera kubvisa zviratidzo.
Kuchengetedzwa kweProzac
Pakave nekukakavara pamusoro pekuchengeteka kweProzac, nekuda kwekudzivirira kwekuchengeteka kweU.S. Food and Drug Administration muna 2007 pamusoro pengozi yekufunga kuzviuraya pakati pemamwe mapoka.
Pasinei nenyevero iyi, Prozac inoramba ichinyorwa uye ingashandiswa zvakachengeteka (kana kuregererwa kana migumisiro yakaipa inokura) apo pasi pekutungamirirwa kwechiremba. Kana iwe uchinetseka pamusoro pekuchengetedzwa kwekutora Prozac, uuye nazvo kuna chiremba wako.
Mishonga Inopindirana
Prozac haifaniri kusanganiswa ne monoamine oxidase inhibitors (MAOIs) kana kutorwa mukati memazuva gumi nemasere pakuramba MAOI. Rega zvisvondo mavhiki mashanu mushure mekurega Prozac usati watanga MAOI. Kushandisa pimozide uye thioridazine kunowedzerawo njodzi inobatanidzwa pakutora Prozac. Mugumisiro wekupindira kwemishonga unogona kunge wakakomba uye unogona kuuraya, saka unofanirwa kukurukura mishonga yose yaunotora nachiremba wako kana chiremba chepfungwa kuti uone kana kuwirirana kungavapo.
Migumisiro Yechiri
Dzimwe mimwe migumisiro yeProzac yakawanda kupfuura dzimwe. Zvimwe zvinokonzerwa nemigumisiro inowanzobatanidza zvinetso zvekurara, kushaya musoro, kuneta, dambudziko, kuora mwoyo, kurasikirwa kwekudya, kushushikana, kuchena kwepabonde, kutengesa, kuputika, dambudziko repabonde, kuvhara muromo, kupisa kwemwoyo, kubuda kwemahara, uye kuonekwa kwakashata. Vamwe vanhu vanocherechedza kuti migumisiro yemigumisiro inononoka kudarika nguva, kana kuti kuderera kuderera.
Zvimwe zvinogona kunge zvisingabatsiri zvinosanganisira kurutsira, kugunun'una, kuputika / mikoko, fivhiri, kuvhara, kufunganya, kunyanya kunetseka, kushungurudzika kufema kana kumedza, kubuda ropa kana kupwanya, uye kuzviuraya pfungwa kana mufambiro. Kana iwe ukawana chimwe cheizvi, iva nechokwadi chekuzivisa chiremba wako kana chiremba chepfungwa.
Ndiani Asingafaniri Kutora Prozac
Prozac inogona kuendeswa kune vacheche panguva yekuzvitakura uye kuburikidza nemukaka wemukaka. Taura nechiremba wako kana uri nepamuviri kana mukoti usati watora Prozac, kuti uone kana zvikomborero zvinopfuura zvengozi.
Kunewo zvimwe zvingangova nengozi kune vanhu vane makore makumi matanhatu nemashanu kana kupfuura avo vanofanirwa kukurukurwa nachiremba wenyu. Kuchengetedzwa nekubudirira kwePrazac yekushandiswa nevana vaduku vane makore gumi nematanhatu hauna kuiswawo.
Kubatana Kwemishonga
Prozac haifaniri kunge yakabatanidzwa newaini, zvimwe zvepamusoro-soro (semuenzaniso aspirin, nemhaka yeropa rekubuda ropa) uye mishonga yemishonga, nemishonga yezvokudya kana maruva (semuenzaniso, St. John's Wort). Iva nechokwadi chekuudza chiremba wako pamusoro pezvose zvauri kutora.
Prozac haifaniri kutorwa panguva imwe chete se monoamine oxidase inhibitors (MAOIs) (pimozide uye thioridazine), tricyclic antidepressants (TCAs), kana zvinodhaka zvinodhindiswa neYP2D6.
Kuchengetedza kunofanira kutorwawo kana ukashandisa pamwe nemishonga inobata hutano hwenheyo (CNS), zvakadai se benzodiazepines.
Manyevero
Kushandisa Prozac kunogona kutakura matambudziko, kusanganisira kukwanisa kwekuchirapa kuchipatara uye muzviitiko zvisingawanzoitiki, kuwedzera pfungwa dzekuzviuraya. Serotonin syndrome inogonawo kuitika, kunyanya kana inoshandiswa pamwe chete nemimwe mishonga. Pedyo nekuongororwa nemunhu wako wepfungwa kana chiremba kunokosha.
Prozac inouyawo neBlack box inonyevera kuti inogona kuwedzera njodzi yekuzviuraya kune vanhu vaduku vanopfuura makore makumi maviri nemashanu. Mune vanhu ava, zvinogona kutungamirira kuzvikonzero zvekuzviuraya, kana kuti kuwedzera kwezvinhu izvi. Kana iwe uri weboka iri, chiremba wako anofanira kukucherechedza iwe, kunyanya mumatanho ekutanga, nekuda kweizvi nyaya huru.
Prozac inogonawo kushandura mania kune vanhu vanoita.
Kubvisa
Prozac inofanira kugara ichidzivirirwa kuti isadzivisa kuregererwa. Kana iwe ukarega kutora Prozac kamwe kamwe, unogona kuona zviratidzo zvakadai sechezzinesi, kuvhiringidzika, manheru, kusuruvara, kusuruvara, kuchema. Nokuda kwechikonzero ichi, usamborega mishonga pasina kubvunza chiremba wako.
Zvimwe Zvingasarudzwa
Kana Prozac isingaregi kubvumira, mamwe maSRR anowanzogadzirirwa kushungurudza anosanganisira Paxil (paroxetine), Lexapro (escitalopram), Luvox CR (fluvoxamine) uye Zoloft (sertraline). Effexor XR (venlafaxine) chimwe chirwere chinonzi anti-depressant chinonzi serotonin-norepinephrine reuptake inhibitor (SNRI) iyo inogona kunge ichibudirira mukurapa kushushikana kwako.
Pakupedzisira, benzodiazepines imwe kirasi yemishonga inowanzoshandiswa pakuzvidya mwoyo, asi inowanzogadziriswa kwenguva pfupi nekuda kwedambudziko ravo rekuvimba. Mishonga inowanikwa mumutambo uyu inosanganisira Valium (diazepam), Xanax (alprazolam), Klonopin (clonazepam) uye Ativan (lorazepam).
Shoko Rinobva
Kana iwe wakagadzirirwa Prozac kuti uzvidye mwoyo, unganzwa uchinetseka nezvemigumisiro yemigumisiro uye kana mishonga ichizobatsira. Taurira chiremba wako zvinetso zvako uye gara uchikurukura pamusoro pezvauri kuita iwe paunotanga mishonga. Kukurukurirana chinhu chinokosha pakuita kuti mishonga inoshandiswa nenzira yakakodzera yekugadzirisa.
Sources:
> Eri Lilly. Prozac Mishonga Gwaro.
> Eri Lilly. Prozac Kurondedzera Mashoko .
> Maya Vetencourt JF, Sale A, Viegi A, et al. Iyo inodzvinyirira inonzi fluoxetine inodzorera mapurasitiki muvanhu vakuru vemaonero cortex. Sayenzi . 2008; 320 (5874): 385-388.
> Medline Plus. Fluoxetine. The American Society of Health-System Pharmacists, Inc. US National Library of Medicine.